Description
The ToupTek E3ISPM45000KPA Microscopy Camera is a professional ultra-high-resolution imaging solution designed for advanced scientific research, industrial inspection, pathology, and precision microscopy applications. As part of the powerful E3ISPM series, this camera combines a large-format Sony CMOS sensor with advanced hardware image processing technology to deliver exceptional image quality, outstanding sensitivity, and reliable performance for demanding microscopy tasks.
Equipped with a 45MP Sony IMX294 back-illuminated CMOS sensor, the E3ISPM45000KPA produces extremely detailed images with a maximum resolution of 8176 × 5616 pixels. The large 4/3-inch sensor format allows a wider field of view and improved light collection efficiency, making the camera highly suitable for capturing fine structures and large specimens with remarkable clarity. The back-illuminated sensor design also improves low-light performance, which is especially valuable for fluorescence microscopy and other challenging imaging conditions.
The camera features a high-speed USB 3.0 interface that ensures fast and stable data transmission for smooth live viewing and responsive operation. Flexible ROI (Region of Interest) functionality enables higher frame rates when monitoring selected image areas, while multiple pixel binning modes help optimize sensitivity and imaging performance for different applications.
ToupTek’s advanced Ultra-Fine hardware ISP engine provides real-time image enhancement including color correction, white balance adjustment, noise reduction, and exposure optimization. This hardware-level processing reduces system load while maintaining excellent color accuracy and sharp image reproduction.
The E3ISPM45000KPA is compatible with a wide range of microscope systems including biological, metallurgical, stereo, and fluorescence microscopes. Its standard C-mount interface allows easy installation on many optical systems and adapters. The durable CNC-machined aluminum housing and fanless design ensure stable long-term operation in laboratory and industrial environments.
With powerful ToupView software support for measurement, stitching, focus stacking, annotation, and video recording, the ToupTek E3ISPM45000KPA is an excellent choice for users seeking professional-grade ultra-high-resolution microscopy imaging.
E3ISPM45000KPA is a digital camera specifically designed for microscopic imaging applications, featuring a IMX294 (C) high-performance image sensor with the following characteristics:
- Exceptional Imaging Quality: 45M (8176×5616) resolution with 2.315 µm × 2.315 µm pixel size, sensor size of 18.93 mm × 13.00 mm , ensuring clear detail presentation
- Imaging Characteristics: Features Rolling Shutter design, supports color imaging, suitable for brightfield, darkfield, phase contrast, fluorescence and other microscopy observation methods
- High-Speed Data Transfer: Utilizes USB3.0 interface with maximum frame rate up to 8.1 fps@8176×5616; 30.0 fps@4088×2808; 8.1 fps@7408×5556; 33.0 fps@4088×2808; 10.4 fps@8176×4320; 34.7 fps@4096×2160; 62.5 fps@2048×1080; 86.5 fps@1344×720 , supporting real-time preview and rapid capture
- Color Reproduction: 8/12-bit color depth with dynamic range reaching TBD , accurately reproducing sample colors
- Sensitivity Performance: Excellent low-light performance with sensitivity of 108 mV with 1/30s; 0.03 mV with 1/30s , suitable for low-light sample observation
- Optical Compatibility: Standard C-mount interface, compatible with various microscope brands, optional 0.5×/0.63×/1× adapters available
- Compact Design: Overall dimensions of only TBD , weighing TBD , powered by USB3.0 interface power (compatible with USB2.0) , no additional power supply required
- Software Support: Includes professional microscopy imaging software ToupView, supports Windows/Linux/macOS/Android multi-platform SDK (native C/C++, C#/VB.NET, Python, Java, DirectShow, TWAIN, etc.) systems, provides measurement, annotation, stitching, focus stacking and other functions, supports C/C++, C#, Python, ImageJ, μManager development environments
ToupTek E3ISPM45000KPA Microscopy Camera Specifications:
| Key Parameters | |
| Model | E3ISPM45000KPA |
| Sensor | IMX294 (C) |
| Effective Pixels / Resolution | 45M (8176×5616) |
| Frame Rate (Full Resolution) | 8.1 fps@8176×5616; 30.0 fps@4088×2808; 8.1 fps@7408×5556; 33.0 fps@4088×2808; 10.4 fps@8176×4320; 34.7 fps@4096×2160; 62.5 fps@2048×1080; 86.5 fps@1344×720 |
| Shutter Type | Rolling Shutter |
| Color Type | Color |
| Imaging Performance | |
| Pixel Size | 2.315 µm × 2.315 µm |
| Sensor Size | 18.93 mm × 13.00 mm |
| Diagonal | 4/3" (22.96 mm) |
| Dynamic Range | TBD |
| Bit Depth | 8/12-bit |
| Sensitivity | 108 mV with 1/30s; 0.03 mV with 1/30s |
| Interface & Mechanical | |
| Data Interface | USB3.0 |
| GPIO | TBD |
| Lens Mount | C-mount |
| Dimensions | TBD |
| Weight | TBD |
| Power Supply | USB3.0 interface power (compatible with USB2.0) |
| Environment & Certification | |
| Operating Temperature / Humidity | -10 °C ~ +50 °C / 30%~80%RH |
| Storage Temperature / Humidity | -20 °C ~ +60 °C / 10%~60%RH |
| Operating System | Windows/Linux/macOS/Android multi-platform SDK (native C/C++, C#/VB.NET, Python, Java, DirectShow, TWAIN, etc.) |
| Certification | CE, FCC |
Package Contents
Standard configuration and packing details for E3ISPM series hardware ISP USB 3.0 CMOS cameras
- Standard Packing List
- Outer carton: L 52 cm × W 32 cm × H 33 cm (20 pcs, approximately 12-17 kg per carton)
- Inner box: L 15 cm × W 15 cm × H 10 cm (0.58-0.60 kg per box)
- One E3ISPM series camera
- High-speed USB 3.0 Type-A to Type-B gold-plated cable (2.0 m)
- CD (drivers and application software, Ø 12 cm)






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